Aimee Ryan, McGill University
Assistant Professor Endocrinology and Metabolism Montreal, Quebec aimee.ryan@mcgill.ca
Expert In
Bio/Research
My lab is interested in understanding how organs are formed and patterned during embryonic development. The pituitary gland originates from an invagination of oral ectoderm (Rathke’s pouch) and the evagination of the infundibulum from the ventral diencephalon (site of the future hypothalamus) wit...
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Bio/Research
My lab is interested in understanding how organs are formed and patterned during embryonic development. The pituitary gland originates from an invagination of oral ectoderm (Rathke’s pouch) and the evagination of the infundibulum from the ventral diencephalon (site of the future hypothalamus) within the first 5 weeks of embryogenesis. Subsequently differentiated cell types appear in response to signalling molecules released from the surrounding tissues and intracellular interactions. In addition, we are studying the function of the homeodomain transcription factor, Pitx2. Mutations in the Pitx2 homeodomain and transactivation domain lead to Rieger’s syndrome, an autosomal dominant disorder which often has associated growth defects.
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