Albert Descoteaux, McGill University
Microbiology and Immunology
Professor
Montreal, Quebec
albert.descoteaux@iaf.inrs.ca
Office:
(450) 687-5010 ext. 4465
Bio/Research
Research Orientations
Because of their potent microbicidal and tumoricidal capacities, macrophages play a major role in the immune response. Macrophage functions are not constitutive, being rather acquired (activation) in the presence of molecules such as cytokines or microbial-derived p...
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Because of their potent microbicidal and tumoricidal capacities, macrophages play a major role in the immune response. Macrophage functions are not constitutive, being rather acquired (activation) in the presence of molecules such as cytokines or microbial-derived p...
Click to Expand >>
Bio/Research
Research Orientations
Because of their potent microbicidal and tumoricidal capacities, macrophages play a major role in the immune response. Macrophage functions are not constitutive, being rather acquired (activation) in the presence of molecules such as cytokines or microbial-derived products. Binding of these molecules at the surface of a resting macrophage triggers intracellular signalling pathways, leading to the induction of gene expression and protein synthesis. These intracellular events culminate in the acquisition of phenotypes allowing the macrophage to perform specific immune functions.
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Because of their potent microbicidal and tumoricidal capacities, macrophages play a major role in the immune response. Macrophage functions are not constitutive, being rather acquired (activation) in the presence of molecules such as cytokines or microbial-derived products. Binding of these molecules at the surface of a resting macrophage triggers intracellular signalling pathways, leading to the induction of gene expression and protein synthesis. These intracellular events culminate in the acquisition of phenotypes allowing the macrophage to perform specific immune functions.
Click to Shrink <<