Andrew Bendall, University of Guelph
Associate Professor
Guelph, Ontario
abendall@uoguelph.ca
Office:
(519) 824-4120 ext. 53491
(519) 824-4120 ext. 56496
Expert In
Cell fate
Chick and mouse development
Chicken embryo
Craniofacial patterning
Embryonic tissues
Evolution of animal bodies
Function of Dlx genes in chondrocyte differentiation
Gene activity
Gene expression
Identifying novel Dlx co-factors
Investigating Dlx-mediated
Mechanisms and action of homeobox family
Morphogenesis
Protien function
Structure-function analyses of Dlx-mediated transcription
Transgenesis in chicken embryos
Vertebrate organisms
Bio/Research
Dr. Bendall's lab is currently investigating the Dlx gene family during chick and mouse development. Homeobox genes encode a large and vitally important family of embryonically expressed transcription factors that regulate the essential processes of development. Unravelling the functions and mech...
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Bio/Research
Dr. Bendall's lab is currently investigating the Dlx gene family during chick and mouse development. Homeobox genes encode a large and vitally important family of embryonically expressed transcription factors that regulate the essential processes of development. Unravelling the functions and mechanisms of action of this multi-member homeobox family promises to reveal larger truths about the cell-type specificity of protein function, the nature of functional redundancy, the acquisition of novel protein functions, and the evolution of animal bodies.
The chicken embryo has a distinguished history in developmental biology as a model vertebrate organism for the ability of investigators to manipulate embryonic tissues and, more recently, levels of gene activity. For Bendall's lab, the chicken embryo holds a central position in their attempts to decipher the mechanisms that regulate gene expression, cell fate, and morphogenesis. The lab combines in vivo experiments like retroviral-mediated transgenesis in chicken embryos with in vitro and cellular studies that, together, define the biochemical basis for biological functions. These studies are often complemented with molecular genetic approaches in the mouse.
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The chicken embryo has a distinguished history in developmental biology as a model vertebrate organism for the ability of investigators to manipulate embryonic tissues and, more recently, levels of gene activity. For Bendall's lab, the chicken embryo holds a central position in their attempts to decipher the mechanisms that regulate gene expression, cell fate, and morphogenesis. The lab combines in vivo experiments like retroviral-mediated transgenesis in chicken embryos with in vitro and cellular studies that, together, define the biochemical basis for biological functions. These studies are often complemented with molecular genetic approaches in the mouse.
Click to Shrink <<