Barbara Lynne Kee, University of Chicago
Professor
Chicago, Illinois
bkee@bsd.uchicago.edu
Office:
(773) 702-4349
Expert In
Bio/Research
The development of mature hematopoietic cells requires the coordinated activity of many transcription factors that regulate differentiation, survival, and proliferation. My lab is interested in understanding how these processes are controlled during commitment of multipotent cells to the lymphoid...
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Bio/Research
The development of mature hematopoietic cells requires the coordinated activity of many transcription factors that regulate differentiation, survival, and proliferation. My lab is interested in understanding how these processes are controlled during commitment of multipotent cells to the lymphoid lineages. We have focused on the basic helix-loop-helix transcription factors encoded by the E2A gene and their antagonists, the Id proteins. E2A proteins are required for B lymphocyte development whereas their antagonist, Id2, is required for Natural Killer cell and lymphoid tissue initiating cell development.
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