Our research focus is on the creation of effective biodegradable and biocompatible polymers for biomedical applications. These applications include localized growth factor delivery for therapeutic angiogenesis and for stem cell differentiation, scaffolds for soft tissue and connective tissue engi...
Our research focus is on the creation of effective biodegradable and biocompatible polymers for biomedical applications. These applications include localized growth factor delivery for therapeutic angiogenesis and for stem cell differentiation, scaffolds for soft tissue and connective tissue engineering, and ocular drug delivery. Polymer systems being developed include biodegradable elastomers, injectable thermoplastics, and hydrogels. We are interested in elucidating the mechanisms of degradation of the polymers in vivo to better design these materials for given applications, determining the mechanisms governing drug release, the role polymer biomaterial mechanical properties play in mediating cell proliferation and differentiation, and in controlling polymer surface properties to improve cellular interactions. The work is multidisciplinary and we collaborate routinely with colleagues in mechanical engineering and cell biology.