Daniela Del Gaudio, University of Chicago
Associate Professor Chicago, Illinois ddelgaudio@bsd.uchicago.edu
Expert In
Bio/Research
Our lab focuses on the rapid translation of new genetic discoveries and innovative technological advancements into clinical tests that can be used to enhance therapeutics and patient treatment strategies, to support the integration of genetics and genomics into clinical practice.
My rese...
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My rese...
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Bio/Research
Our lab focuses on the rapid translation of new genetic discoveries and innovative technological advancements into clinical tests that can be used to enhance therapeutics and patient treatment strategies, to support the integration of genetics and genomics into clinical practice.
My research interests relate to the molecular genetics of endocrine disorders with a focus on monogenic disorders of insulin secretion, such as monogenic forms of diabetes, congenital hyperinsulinism and familial forms of lipodystrophy. Our laboratory has been a leader in developing diagnostics for monogenic disorders of insulin secretion, launching the first tests for monogenic diabetes in 2013 and continuously expanding and refining these panels as new genes and phenotypes are identified. As an extension of this work, I have branched out in other endocrine disorders with a monogenic etiology, including obesity and disorders of sex development and differentiation. We are using an integrated approach using targeted next-generation sequencing panels, exome sequencing and microarray analyses to determine the molecular basis of these diseases, with the ultimate goal to develop better diagnostic tools and more effective personalized therapeutic approaches. I also direct the Clinical Molecular Genetics training program at the University of Chicago.
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My research interests relate to the molecular genetics of endocrine disorders with a focus on monogenic disorders of insulin secretion, such as monogenic forms of diabetes, congenital hyperinsulinism and familial forms of lipodystrophy. Our laboratory has been a leader in developing diagnostics for monogenic disorders of insulin secretion, launching the first tests for monogenic diabetes in 2013 and continuously expanding and refining these panels as new genes and phenotypes are identified. As an extension of this work, I have branched out in other endocrine disorders with a monogenic etiology, including obesity and disorders of sex development and differentiation. We are using an integrated approach using targeted next-generation sequencing panels, exome sequencing and microarray analyses to determine the molecular basis of these diseases, with the ultimate goal to develop better diagnostic tools and more effective personalized therapeutic approaches. I also direct the Clinical Molecular Genetics training program at the University of Chicago.
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