Development of models, algorithms and statistical inference procedures for the comparative analysis of gene order in different genomes.
RESEARCH RELEVANCE
Understanding the principles by which genomes change and evolve.
David Sankoff is known as one of the founding fathers of bioinformatics and computational biology. David Sankoff has been at the origin of numerous fields in bioinformatics, starting with the fundamental problem of sequence alignment. In particular, he contributed to the early introduction of dynamic programming to computational biology. David has the reputation of asking the right questions, of being visionary, and of laying the foundations of numerous fields in comparative genomics, such as: sequence alignment, RNA folding, phylogeny reconstruction, gene order rearrangement, and long-term genomic evolution.