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Bio/Research
Cell surface receptor proteins and secreted protein ligands determine the specific connectivity of cells which drives the development of complex systems and organs in multicellular organisms. Our laboratory is interested in the function and biochemistry of the network of proteins that are require...
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Bio/Research
Cell surface receptor proteins and secreted protein ligands determine the specific connectivity of cells which drives the development of complex systems and organs in multicellular organisms. Our laboratory is interested in the function and biochemistry of the network of proteins that are required for the development and function of such complex structures. Specifically, we are working on deciphering protein-protein interaction networks of the extracellular space, especially in the nervous system. We also study these proteins biochemically to understand the signaling mechanisms that lead to cellular and subcellular specializations, such as synapses. As a tool, we are heavily using x-ray crystallography to understand protein function.
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