Giovanni (John) Di Battista, McGill University

Profile photo of Giovanni (John) Di Battista, expert at McGill University

Department of Medicine Division of Experimental Medicine Professor Montreal, Quebec john.dibattista@mcgill.ca Office: (514) 934-1934 ext. 34401

Bio/Research

Our research program is focused on the cellular (signaling) and molecular (gene regulation) mechanisms regulating the various components of the inflammatory response using both in vitro and in vivo experimental approaches. The studies have elucidated novel mechanisms involving highly coordinated ...

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Bio/Research

Our research program is focused on the cellular (signaling) and molecular (gene regulation) mechanisms regulating the various components of the inflammatory response using both in vitro and in vivo experimental approaches. The studies have elucidated novel mechanisms involving highly coordinated post-transcriptional and translational control of target genes (e.g. TNF-_, IL-1ß, etc.). In addition, we have revealed the level to which signaling cascades are integrated (scaffolding) in the coordination of cellular responses to inflammatory (extracellular) stimuli. This research program has provided the conceptual framework for identifying new therapeutic targets for the treatment of arthritis and related inflammatory diseases.

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