Giovanni (John) Di Battista, McGill University
Department of Medicine
Division of Experimental Medicine
Professor
Montreal, Quebec
john.dibattista@mcgill.ca
Office:
(514) 934-1934 ext. 34401
Expert In
Bio/Research
Our research program is focused on the cellular (signaling) and molecular (gene regulation) mechanisms regulating the various components of the inflammatory response using both in vitro and in vivo experimental approaches. The studies have elucidated novel mechanisms involving highly coordinated ...
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Bio/Research
Our research program is focused on the cellular (signaling) and molecular (gene regulation) mechanisms regulating the various components of the inflammatory response using both in vitro and in vivo experimental approaches. The studies have elucidated novel mechanisms involving highly coordinated post-transcriptional and translational control of target genes (e.g. TNF-_, IL-1ß, etc.). In addition, we have revealed the level to which signaling cascades are integrated (scaffolding) in the coordination of cellular responses to inflammatory (extracellular) stimuli. This research program has provided the conceptual framework for identifying new therapeutic targets for the treatment of arthritis and related inflammatory diseases.
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