Glenn Randall, University of Chicago
Associate Professor Chicago, Illinois grandall@bsd.uchicago.edu
Expert In
Bio/Research
Glenn's laboratory investigates the roles of virus-host interactions in replication and pathogenesis. They study viruses of the Flaviviridae, including hepatitis C virus and dengue virus. By applying RNAi interference as a genetic approach to identify host genes required for HCV infection, they h...
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Bio/Research
Glenn's laboratory investigates the roles of virus-host interactions in replication and pathogenesis. They study viruses of the Flaviviridae, including hepatitis C virus and dengue virus. By applying RNAi interference as a genetic approach to identify host genes required for HCV infection, they have identified ~75 host cofactors of replication. They now study the importance of these cellular genes in diverse steps of the viral life cycle, including entry, the regulation of viral protein translation and RNA replication, modulation of cellular lipid metabolism, the establishment of viral replication complexes, the secretion of infectious virus, and control of infection by the innate immune system.
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