Glenn Randall, University of Chicago

Profile photo of Glenn Randall, expert at University of Chicago

Associate Professor Chicago, Illinois grandall@bsd.uchicago.edu

Bio/Research

Glenn's laboratory investigates the roles of virus-host interactions in replication and pathogenesis. They study viruses of the Flaviviridae, including hepatitis C virus and dengue virus. By applying RNAi interference as a genetic approach to identify host genes required for HCV infection, they h...

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Bio/Research

Glenn's laboratory investigates the roles of virus-host interactions in replication and pathogenesis. They study viruses of the Flaviviridae, including hepatitis C virus and dengue virus. By applying RNAi interference as a genetic approach to identify host genes required for HCV infection, they have identified ~75 host cofactors of replication. They now study the importance of these cellular genes in diverse steps of the viral life cycle, including entry, the regulation of viral protein translation and RNA replication, modulation of cellular lipid metabolism, the establishment of viral replication complexes, the secretion of infectious virus, and control of infection by the innate immune system.

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