Our group is broadly interested in the chemistry and biochemistry of nucleic acids with particular emphasis on RNA catalysis and structure. The laboratory integrates areas of organic chemistry, physical chemistry, enzymology and molecular biology to gain a fundamental understanding of nucleic aci...
Our group is broadly interested in the chemistry and biochemistry of nucleic acids with particular emphasis on RNA catalysis and structure. The laboratory integrates areas of organic chemistry, physical chemistry, enzymology and molecular biology to gain a fundamental understanding of nucleic acid structure and mechanisms of RNA catalysis. Using the principles and techniques of organic chemistry and molecular biology, we manipulate the structure of RNA molecules at precise locations in ways that are designed to answer very specific questions about biological function.