Studying the factors controlling fat (adipose tissue) storage.
RESEARCH RELEVANCE
Gaining a better understanding of the causes of obesity and lipodystrophy and their metabolic symptoms.
Obese people have much higher rates of insulin resistance, diabetes, and cardiovascular and respiratory diseases. Katherine Cianflone pioneered research on the adipokine ASP, a protein that stimulates fat synthesis. The goals of her work are to identify and characterize in greater detail and with greater precision the adipokines that may influence fat storage, to examine the physiological changes caused by them, and to develop weight-gain prevention strategies.