Laura Trinkle-Mulcahy, University of Ottawa

Profile photo of Laura Trinkle-Mulcahy, expert at University of Ottawa

Assistant Professor Cellular and Molecular Medicine Ottawa, Ontario ltrinkle@uottawa.ca Office: (613) 562-5800 ext. 8068

Bio/Research

Ongoing projects in the lab include identifying and characterizing PP1 targeting subunits and determining isoform specificity, if any. We are also continuing to study the targeting of RepoMan/PP1 to chromosome-associated substrates throughout the cell cycle, and that of other novel PP1 complexes ...

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Bio/Research

Ongoing projects in the lab include identifying and characterizing PP1 targeting subunits and determining isoform specificity, if any. We are also continuing to study the targeting of RepoMan/PP1 to chromosome-associated substrates throughout the cell cycle, and that of other novel PP1 complexes identified in our SILAC IP screens of GFP-PP1 in nuclear and cytoplasmic extracts. As one of only a handful of labs using this combined approach of cell biology, biochemistry and quantitative proteomics, we feel confident that we will continue to general novel and exciting data that will help to unravel the intricacies of PP1 regulation in mammalian cells.

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