Leonard Maler, University of Ottawa
Cellular & Molecular Medicine
Professor
Ottawa, Ontario
lmaler@uottawa.ca
Office:
(613) 562-5800 ext. 8189
Expert In
Bio/Research
All sensory systems of vertebrates have extensive feedback input, but its function is still obscure. Dr. Maler's research has focused on feedback input in the electrosensory system, which is especially amenable to detailed analysis at both the circuit and cellular levels. Morphological, electroph...
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Bio/Research
All sensory systems of vertebrates have extensive feedback input, but its function is still obscure. Dr. Maler's research has focused on feedback input in the electrosensory system, which is especially amenable to detailed analysis at both the circuit and cellular levels. Morphological, electrophysiological, and computational techniques are used to investigate how the patterns of connectivity, the properties of neuronal ion channels and the behaviour of modifiable synapses act in concert to allow feedback input to modulate the spatio-temporal filtering of sensory systems.
A second project of this group is to examine the cellular properties of a neuronal group which controls aggressive and reproductive communication in electric fish. Immunohistochemical and electrophysiological techniques are used to study the interactions of transmitters (peptides and amino acids) and intrinsic voltage-sensitive ion channels in determining the quality of the communicatory output. A major goal of these investigations is to identify the cellular basis of the seasonal variations in aggressive/reproductive communication.
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A second project of this group is to examine the cellular properties of a neuronal group which controls aggressive and reproductive communication in electric fish. Immunohistochemical and electrophysiological techniques are used to study the interactions of transmitters (peptides and amino acids) and intrinsic voltage-sensitive ion channels in determining the quality of the communicatory output. A major goal of these investigations is to identify the cellular basis of the seasonal variations in aggressive/reproductive communication.
Click to Shrink <<