Research in Dr. Alpaugh’s lab focuses on understanding the role of protein misfolding to common degenerative disorders of the brain such as Alzheimer’s disease and Parkinson’s disease, with a specific focus on Huntington’s disease.
One particular area of interest is in understanding the ...
Research in Dr. Alpaugh’s lab focuses on understanding the role of protein misfolding to common degenerative disorders of the brain such as Alzheimer’s disease and Parkinson’s disease, with a specific focus on Huntington’s disease.
One particular area of interest is in understanding the interplay between disease-associated proteins and the blood-brain barrier, an important interface between the brain and the rest of the body. To facilitate this research, Alpaugh has developed a 3D cell culture model of the human blood-brain barrier.