Professor Wu's research lab studies molecular mechanisms with which cells sense and migrate, using an integrated microsystems engineering and theoretical modeling approach. She and her students develop microfluidic systems to provide cells with well-defined and physiologically realistic 3D microe...
Professor Wu's research lab studies molecular mechanisms with which cells sense and migrate, using an integrated microsystems engineering and theoretical modeling approach. She and her students develop microfluidic systems to provide cells with well-defined and physiologically realistic 3D microenvironments (e.g., chemical gradients, fluid flows, and biomatrices). They also develop and utilize advanced microscopic imaging systems to quantify cellular dynamics. Their current focus is on the roles of tumor cell microenvironment in cancer cell chemoinvasion and its implications in cancer metastasis.