Moshmi Bhattacharya, Western University
Assistant Professor
Physiology and Pharmacology
London, Ontario
moshmi.bhattacharya@schulich.uwo.ca
Office:
(519) 661-2111 ext. 82970
Expert In
Bio/Research
I grew up on the sunny island of Trinidad in the Caribbean.
I obtained my BSc degree from the University of West Indies (Biochemistry, Faculty of Natural Sciences, 1992). Next, I married my wonderful husband and sampled life in five North American cities; conclusion: Winnipeg is really ...
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I obtained my BSc degree from the University of West Indies (Biochemistry, Faculty of Natural Sciences, 1992). Next, I married my wonderful husband and sampled life in five North American cities; conclusion: Winnipeg is really ...
Click to Expand >>
Bio/Research
I grew up on the sunny island of Trinidad in the Caribbean.
I obtained my BSc degree from the University of West Indies (Biochemistry, Faculty of Natural Sciences, 1992). Next, I married my wonderful husband and sampled life in five North American cities; conclusion: Winnipeg is really cold, Illinois grows a lot of corn, Minnesota's Mall of America is as large as they say, Montreal is absolutely divine and London is home.
I was awarded my PhD degree from McGill University (Pharmacology and Therapeutics, 1995-1999): The vibrant research atmosphere I experienced there led to my desire to pursue a life of medical research; hoping that everything I do will make a difference in a patient's life. Outside the research lab, I enjoy: swimming, hiking, gardening, astronomy, movies and reading murder mysteries. However, currently my spare time is largely taken up being Mom.
The Bhattacharya laboratory program is focused on understanding the molecular mechanisms regulating breast cancer cell migration and invasion, processes required for metastasis. In Canadian women, breast cancer is the most frequently diagnosed cancer, accounting for an estimated 30% of all cancer cases. The high mortality rate from breast cancer is largely due to the metastatic spread of the disease and therefore suppression of metastasis is an important issue in the treatment of the disease. However, the underlying mechanism(s) regulating metastasis are largely unknown. We are interested in how the signaling and trafficking of G protein-coupled receptors regulates breast cancer metastasis, using various molecular and biochemical techniques to study gene expression and protein-protein interactions in cancer cells. We also use fluorescent reporter molecules to study receptor-mediated intracellular signalling events in real-time, in single live cells and visualized by laser scanning confocal microscopy. The research program is comprised of the following projects:
1. Lipid signaling in breast cancer
2. Crosstalk between GPCRs and growth-factor receptors in cancer
3. Regulation of cancer cell cytoskeleton by small GTPases
Recent research has demonstrated that approaches that take into account the signaling aspects of receptor systems are essential for cancer chemotherapies. These studies will provide a better understanding of the molecular events of the metastatic process and may reveal novel molecular targets for the design of more effective therapeutics
Click to Shrink <<
I obtained my BSc degree from the University of West Indies (Biochemistry, Faculty of Natural Sciences, 1992). Next, I married my wonderful husband and sampled life in five North American cities; conclusion: Winnipeg is really cold, Illinois grows a lot of corn, Minnesota's Mall of America is as large as they say, Montreal is absolutely divine and London is home.
I was awarded my PhD degree from McGill University (Pharmacology and Therapeutics, 1995-1999): The vibrant research atmosphere I experienced there led to my desire to pursue a life of medical research; hoping that everything I do will make a difference in a patient's life. Outside the research lab, I enjoy: swimming, hiking, gardening, astronomy, movies and reading murder mysteries. However, currently my spare time is largely taken up being Mom.
The Bhattacharya laboratory program is focused on understanding the molecular mechanisms regulating breast cancer cell migration and invasion, processes required for metastasis. In Canadian women, breast cancer is the most frequently diagnosed cancer, accounting for an estimated 30% of all cancer cases. The high mortality rate from breast cancer is largely due to the metastatic spread of the disease and therefore suppression of metastasis is an important issue in the treatment of the disease. However, the underlying mechanism(s) regulating metastasis are largely unknown. We are interested in how the signaling and trafficking of G protein-coupled receptors regulates breast cancer metastasis, using various molecular and biochemical techniques to study gene expression and protein-protein interactions in cancer cells. We also use fluorescent reporter molecules to study receptor-mediated intracellular signalling events in real-time, in single live cells and visualized by laser scanning confocal microscopy. The research program is comprised of the following projects:
1. Lipid signaling in breast cancer
2. Crosstalk between GPCRs and growth-factor receptors in cancer
3. Regulation of cancer cell cytoskeleton by small GTPases
Recent research has demonstrated that approaches that take into account the signaling aspects of receptor systems are essential for cancer chemotherapies. These studies will provide a better understanding of the molecular events of the metastatic process and may reveal novel molecular targets for the design of more effective therapeutics
Click to Shrink <<