Nozomi Nishimura, Cornell University
Assistant Professor
Ithaca, New York
nn62@cornell.edu
Office:
(607) 342-7738
Expert In
Bio/Research
I am interested in how the vasculature, immune, inflammatory systems and cells native to a tissue interact in disease states. Our strategy is to develop novel tools to image the contribution of multiple physiological systems to diseases with in vivo animal models. To study these systems at their ...
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Bio/Research
I am interested in how the vasculature, immune, inflammatory systems and cells native to a tissue interact in disease states. Our strategy is to develop novel tools to image the contribution of multiple physiological systems to diseases with in vivo animal models. To study these systems at their full complexity in the complete living animal, we use multiphoton microscopy to image cell dynamics in rodents. We also use femtosecond laser ablation and quantitative analysis to dissect function in the living system. In diseases as diverse as cardiovascular disease and cancer metastasis, the microvasculature provides an avenue of access for immune and inflammatory cells. Alterations in blood flow and the invasion of blood-borne cells are examples of complex events which can shape how a disease either progresses or resolves. We compare these dynamics across multiple organ systems and diseases.
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