Sally Horne-Badovinac, University of Chicago
Associate Professor
Chicago, Illinois
shorne@uchicago.edu
Office:
(773) 834-1471
Expert In
Bio/Research
During development, discrete organs and entire body plans emerge from the coordinate actions of individual cells. These complex morphogenetic events require dynamic regulation of cell shape, polarity and adhesion across cell populations. Our lab seeks to understand how these diverse cellular beha...
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Bio/Research
During development, discrete organs and entire body plans emerge from the coordinate actions of individual cells. These complex morphogenetic events require dynamic regulation of cell shape, polarity and adhesion across cell populations. Our lab seeks to understand how these diverse cellular behaviors are orchestrated to produce an organ's functional shape.
To this end, we are using genetic, cell biological and live imaging approaches in Drosophila to investigate how a simple, ovarian structure called and egg chamber lengthens as it grows. We are particularly interested in the roles that collective cell migration and basement membrane remodeling play in this process. Please visit our lab website for more information about the strengths of this system and the specific questions that we pursue.
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To this end, we are using genetic, cell biological and live imaging approaches in Drosophila to investigate how a simple, ovarian structure called and egg chamber lengthens as it grows. We are particularly interested in the roles that collective cell migration and basement membrane remodeling play in this process. Please visit our lab website for more information about the strengths of this system and the specific questions that we pursue.
Click to Shrink <<