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Bio/Research
Translational regulation is related to the dynamic properties of tRNA that constantly change to facilitate stress response and adaptation to new environments and to control gene expression. We developed microarray and high-throughput sequencing methods that measure tRNA abundance, fraction of ami...
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Bio/Research
Translational regulation is related to the dynamic properties of tRNA that constantly change to facilitate stress response and adaptation to new environments and to control gene expression. We developed microarray and high-throughput sequencing methods that measure tRNA abundance, fraction of aminoacylation, misacylation and modification dynamics at the transcriptomic scale. We are exploring roles of tRNA in translational control in mammalian cells.
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